Side Effects of a Single Shot Intrathecal Morphine in Clinical Practice, a Retrospective Analysis

ITM has the potential to be a powerful tool for multimodal postoperative pain management, understanding, preventing and managing its side effects is crucial for upturn of patient safety and comfort. This retrospective audit will therefore be focused on the most reported side effects in daily clinical practice in patients having received ITM. The results of this study may lead to new insights into the clinically relevant risk-benefit balance of ITM and will contribute to the optimisation of its use in clinical practice.

NCT Number	NCT07238179
Lead Sponsor	Universitaire Ziekenhuizen KU Leuven
Conditions	Morphine, Morphine Adverse Reaction, Morphine Induced Pruritis, Nausea and Vomiting, Postoperative, Analgesia, Spinal Analgesia
Enrollment	600 participants
Start Date	2021-03-01
Primary Completion	2025-12-31 (estimated)
Study Completion	2026-07-31 (estimated)
Updated on ClinicalTrials.gov	2026-05-05