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The Effect of Different Intracanal Medicaments on Periapical Lesion Healing

StatusRecruiting
PhaseNot applicable
Started
View on ClinicalTrials.gov ↗
Trial flagged as At Risk
Primary completion moved at least 7 months later Sep 1, 2026 → Apr 1, 2027
See other at-risk trials from Mustafa Kemal University

Record History

  1. Primary completion pushed from Sep 1, 2026 to Apr 1, 2027
    • Publications: details revised at 4 of 4 entries
  2. Primary completion date: Apr 1, 2026 to Sep 1, 2026v2
  3. Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
This study is planned to evaluate the effects of two different intracanal medicaments-calcium hydroxide and diclofenac sodium-on periapical healing following endodontic retreatment. Fifty-four patients will be included and randomly assigned into two groups according to the type of medicament used. All procedures will be performed by a single experienced endodontist under standardized clinical conditions. Periapical lesion healing will be assessed radiographically at baseline and after 12 months using fractal analysis to quantitatively evaluate bone regeneration. The primary outcome will be the change in the fractal dimension values between the initial and follow-up radiographs.
Trial Details
NCT Number NCT07237620
Lead Sponsor Mustafa Kemal University
Conditions
(from sponsor)		 Periapical Lesion Healing, Apical Periodontitis
Related terms Periapical Periodontitis
Enrollment 60 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov