Clinical Trial

Paracetamol and Mannitol Injection and Postoperative Delirium

Name: Paracetamol and Mannitol Injection and Postoperative Delirium — clinical trial record (NCT07235995)
Creator: DataLookout
License: https://creativecommons.org/licenses/by/4.0/

Study acronym: PAPOD-ES

Not Yet Recruiting Phase 4

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Summary

The aim of this multi-center RCT is to investigate the effect of intravenous acetaminophen (paracetamol and mannitol injection) on postoperative delirium, comparing with intravenous sufentanil, in elderly noncardiac surgical patients admitted to ICU.

Trial Details

NCT Number	NCT07235995
Lead Sponsor	Xiangya Hospital of Central South University
Conditions	Postoperative Delirium, Elderly, Non Cardiac Surgery
Enrollment	1,092 participants
Start Date	2025-12-01
Primary Completion	2027-01-31 (estimated)
Study Completion	2027-04-30 (estimated)
Updated on ClinicalTrials.gov	2025-11-19