Implementation of Intensive Hypertension Management Approaches: Cleveland Clinic

The primary objective of the Implementation of Effective Hypertension Management Approaches: Cleveland Clinic program is to improve blood pressure control for patients diagnosed with hypertension (HTN) and uncontrolled blood pressure, specifically defined as a blood pressure greater than 150/95, across all Cleveland Clinic Northeast Ohio primary care practices. The project will scale up the availability of resources for treating hypertension in 56 primary care practices within the Cleveland Clinic Health System in Northern Ohio, reaching up to approximately 3800 patients. This project will utilize evidence from a randomized controlled trial by Margolis et al.(1) to build upon Cleveland Clinic's existing team-based primary care provider (PCP) collaboration with pharmacists and advanced practice providers (APP) and will use a mechanism that allows titrating blood pressure medications based on patient-recorded home blood pressure readings.

NCT Number	NCT07232017
Lead Sponsor	Anita Misra-Hebert Collaborators: Patient-Centered Outcomes Research Institute, The Cleveland Clinic
Conditions	Hypertension (HTN)
Enrollment	1,520 participants
Start Date	2026-01-06
Primary Completion	2029-04 (estimated)
Study Completion	2029-07 (estimated)
Updated on ClinicalTrials.gov	2026-01-09