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Chlordecone Exposure and Female Fertility

Study acronym: KARU-FERTIL
StatusRecruiting
PhaseNot specified
Started
View on ClinicalTrials.gov ↗
Record status
This record was last updated November 17, 2025 (before its estimated January 26, 2026 completion). Its status may not reflect the trial's current state.

Record History

  1. Study First Submitted
Chlordecone is an organochlorine pesticide used in the French West Indies (FWI) from 1972 to 1993 to control the banana root borer. Due to its very long persistence the population continues to be exposed to this chemical through their food consumptions. Although, chlordecone have been associated in animal study impairment of ovarian reserve, to date, no study has been published concerning the link between chlordecone exposure and female fertility. The main objective of this project is to study the association between chlordecone exposure and anti-mullerian hormone (AMH) in women consulting for couple infertility in Guadeloupe.
Trial Details
NCT Number NCT07231510
Lead Sponsor Centre Hospitalier Universitaire de la Guadeloupe
Collaborators: Institut Pasteur de Guadeloupe, Rennes University Hospital
Conditions
(from sponsor)		 Infertility Female
Related terms Endometriosis, Infertility, Female, Polycystic Ovary Syndrome
Enrollment 634 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov