Sepsis-associated Thrombocytopenia and Platelet Transfusion （STAPT）

Currently, there are no multicenter studies on platelet transfusion for SAT patients, and the benefits and risks of platelet transfusion still require further validation based on large-sample data. In summary, investigating the correlation between platelet transfusion during ICU stay and 28-day mortality in SAT patients, as well as evaluating the impact of platelet transfusion on bleeding, thrombotic events, and inflammation control, is of great significance for optimizing SAT management strategies. This study aims to analyze the effect of platelet transfusion on the prognosis of SAT patients, thereby providing an evidence-based foundation for clinical decision-making.

NCT Number	NCT07230067
Lead Sponsor	Nanfang Hospital, Southern Medical University
Conditions	Sepsis, Sepsis and Coagulopathy
Enrollment	1,500 participants
Start Date	2025-11-15
Primary Completion	2026-12-30 (estimated)
Study Completion	2027-03-31 (estimated)
Updated on ClinicalTrials.gov	2026-01-30