INSPIRatory Efforts Estimation Under High-flow Nasal Oxygen

High-flow nasal oxygen (HFNO) is recommended as first-line treatment to prevent intubation in acute hypoxemic respiratory failure and to prevent reintubation after extubation. Accumulating data suggest that strong inspiratory efforts and their persistence are associated with HFNO failure. However, tools to monitor continuously and noninvasively inspiratory efforts are lacking. The investigators have developed an algorithm estimating noninvasively inspiratory efforts under HFNO. This pilot study aims at testing the feasibility of estimating inspiratory efforts in patients treated with HNFO.

NCT Number	NCT07228676
Lead Sponsor	Poitiers University Hospital
Conditions	Oxygen, Respiratory Insufficiency, Work of Breathing, Dyspnea
Enrollment	20 participants
Start Date	2025-11-29
Primary Completion	2026-03-13 (estimated)
Study Completion	2026-04-09 (estimated)
Updated on ClinicalTrials.gov	2026-05-22