Clinical Trial

Endothelial Dysfunction After SCI

Study acronym: EDASCI
Recruiting
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Summary
This study plans to learn how endothelial cells, single cell lining of blood vessels may be dysfunctional after a spinal cord injury. Endothelial dysfunction will be measured by the capacity of blood vessels to vasodilate (increase in size) and alter blood flow is lower in adults with a spinal cord injury in comparison to adults without a spinal cord injury. The mechanisms which may alter this function may be critical in reducing the risk of heart attacks and strokes in people with spinal cord injuries.
Protocol Amendment History 1 amendment
This ClinicalTrials.gov record has been amended once since 2025-11-11.
Trial Details
NCT Number NCT07227727
Lead Sponsor Craig Hospital
Collaborators: University of Colorado, Boulder, Denver Health and Hospital Authority
Conditions Spinal Cord Injuries, Endothelial Dysfunction
Enrollment 40 participants
Start Date 2025-07-31
Primary Completion 2027-07-30 (estimated)
Study Completion 2027-07-30 (estimated)
Updated on ClinicalTrials.gov 2025-11-14