Non-Abstinence Outcomes in Methamphetamine Use Disorder

Reduced drug use is a clinically meaningful target for treatment development, but few studies have evaluated the positive impacts produced by this behavioral change, preventing adoption of this endpoint in clinical trials. The proposed research will fill that critical knowledge gap by demonstrating the biopsychosocial benefits of reduced methamphetamine use. These data will be used to change current accepted methamphetamine treatment endpoints and accelerate identification of therapies for methamphetamine use disorder.

NCT Number	NCT07226596
Lead Sponsor	William Stoops Collaborators: National Institute on Drug Abuse (NIDA)
Conditions	Methamphetamine Use Disorder
Enrollment	300 participants
Start Date	2026-01-14
Primary Completion	2031-01-04 (estimated)
Study Completion	2031-01-04 (estimated)
Updated on ClinicalTrials.gov	2026-06-08