Dietary Interventions to Reduce Ultra-Processed Food Intake

The DISRUPT clinical trial will test two different 2-month programs to help adults with overweight/obesity (N=60) reduce their intake of ultra-processed foods (UPFs). Participants will be randomly assigned to receive standard dietary change strategies, cognitive dissonance strategies that engage them in activism against the UPF industry, or both. All participants will attend an introductory educational workshop about UPFs. If they are assigned to receive one or more of these strategies, they will attend weekly group sessions with the relevant intervention content for 7 more weeks. Groups will be held virtually.

NCT Number	NCT07226336
Lead Sponsor	Oregon Research Institute Collaborators: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), Albert Einstein College of Medicine
Conditions	Ultra-Processed Food Intake, Obesity & Overweight
Enrollment	60 participants
Start Date	2026-02
Primary Completion	2026-08 (estimated)
Study Completion	2026-08 (estimated)
Updated on ClinicalTrials.gov	2025-11-10