Clinical Trial

CLF065 for Chronic Pouchitis

Study acronym: OPUS

Suspended Phase 2

View on ClinicalTrials.gov →

Why the trial stopped

Clinical Hold

Summary

This clinical trial is to evaluate investigational compound CLF065 as a treatment for adult patients with chronic pouchitis. The goals are to establish the safety, feasibility and efficacy of weekly dosing of long acting CLF065 versus placebo.

Protocol Amendment History 2 changes

critical Recruitment suspended 2026-07-10

critical Reason stopped changed: — → Clinical Hold 2026-07-10

Trial Details

NCT Number	NCT07226050
Lead Sponsor	Calibr, a division of Scripps Research
Conditions	Pouchitis
Enrollment	20 participants
Start Date	2026-06-01
Primary Completion	2027-03 (estimated)
Study Completion	2027-06 (estimated)
Updated on ClinicalTrials.gov	2026-07-09