Clinical Trial

A Trial to Investigate the Safety and Efficacy of Intra-articular 4P004 Injection in Subjects With Knee Synovitis and Osteoarthritis

Study acronym: INFLAM MOTION
Active, Not Recruiting Phase 2
View on ClinicalTrials.gov →
Summary
This phase 2a trial is an international, multicenter, randomized, double-blind, placebo-controlled trial to investigate the efficacy and safety of one single intra-articular (IA) injection of 4P004 or placebo in: * patients between 40 and 80 years of age, * with synovitis and grade 2 to 4 osteoarthritis (OA) of the knee according to Kellgren and Lawrence (KL) classification.
Protocol Amendment History 2 changes
critical Enrollment closed, study ongoing 2026-07-28
notable Primary completion pushed: 2026-07 -> 2026-08-28 2026-07-28
Trial Details
NCT Number NCT07225829
Lead Sponsor 4Moving Biotech
Conditions Knee Osteoarthritis, Synovitis of Knee
Enrollment 129 participants
Start Date 2025-06-17
Primary Completion 2026-08-28 (estimated)
Study Completion 2026-09 (estimated)
Updated on ClinicalTrials.gov 2026-07-27