A Study of BI 3810944 in Patients With Advanced Cancer

This study is open to adults with advanced cancer (solid tumours) for whom previous treatment was not successful, or no treatment exists. The study tests different doses of BI 3810944 to find out which doses they can tolerate. Another purpose is to identify the most suitable dose of BI 3810944 and to find out whether it helps people with advanced cancer. BI 3810944 may help fight cancer. Participants get BI 3810944 usually once every 3 weeks. At treatment start, it is given once a week for a short time. Participants may continue to get BI 3810944 as long as they benefit from treatment but no longer than 2 years. During this time, they regularly visit the study site. The first study visits include overnight stays at the hospital. At the visits, study doctors check participants' health, take necessary laboratory tests, and note any unwanted effects. The doctors also regularly check the size of the tumour with imaging methods.

NCT Number	NCT07224425
Lead Sponsor	Boehringer Ingelheim
Conditions	Solid Tumours, Melanoma
Enrollment	69 participants
Start Date	2026-02-24
Primary Completion	2029-10-05 (estimated)
Study Completion	2029-10-05 (estimated)
Updated on ClinicalTrials.gov	2026-07-22