Multi-Modal Monitoring of Disease Symptoms in Myasthenia Gravis

Evaluate the feasibility of using digital health technologies to monitor symptoms in myasthenia gravis (MG). Study subjects will be screened and enrolled at Massachusetts General Brigham Hospital to participate in this 12 month observational study. Study subjects will be asked to wear multiple wearable sensors to monitor their physical activity and PPG during daily activities. Participants will also complete speech, video, and ePRO and eCOA digital assessments at home and during study visits. The primary objective for this observational study is to measure the correlation of sensor-derived measures of physical activity to MG-specific ratings of MG-ADL, QMG, MGC, and Neuro-QoL Fatigue

NCT Number	NCT07224386
Lead Sponsor	BioSensics Collaborators: National Institute of Neurological Disorders and Stroke (NINDS), Massachusetts General Hospital
Conditions	Myasthenia Gravis, Myasthenia Gravis, Generalized
Enrollment	50 participants
Start Date	2026-01-01
Primary Completion	2027-12-31 (estimated)
Study Completion	2028-04-30 (estimated)
Updated on ClinicalTrials.gov	2025-11-04