The Impact of Physiologic Cataract Surgery on Patient Comfort and Medication Usage

The study will pertain to investigating the impact of high vs low IOP on the intraoperative experience and comfort for the patient and surgeon. Our hypothesis is that operating at a more physiological IOP using Unity VCS/CS and Centurion with Active Sentry at a higher, or more traditional IOP will result in significantly less discomfort/pain as assessed by the decreased need for rescue medication and lower VAS scores.

NCT Number	NCT07223866
Lead Sponsor	Matthew Rauen
Conditions	Cataract and IOL Surgery, Cataract Surgery Anesthesia, Cataract Surgery Experience, Nuclear Cataract
Enrollment	85 participants
Start Date	2025-11-01
Primary Completion	2026-11-01 (estimated)
Study Completion	2027-01-01 (estimated)
Updated on ClinicalTrials.gov	2025-11-10