Gastrointestinal Response of Pediatric Cystic Fibrosis Patients on Mediterranean Diet

There is no study to date that has evaluated the impact or effect of a Mediterranean diet in children with CF. The goal of this study would be to help provide better guidance around questions the investigators, as CF care providers continue to receive from patients and families about how to best promote overall health in pediatric cystic fibrosis from a dietary perspective. Currently, the updated nutritional recommendations are variable and broad. Parents continue to search for more concrete guidance about how best to promote long-term health given the ever-increasing life expectancy of cystic fibrosis patients in this new area of advanced therapeutics. Given the changing landscape of the CF care in general, children are less likely to struggle with early life malnutrition, and it is becoming increasingly clear that high fat, high calorie diets are not beneficial nor are necessary for all children with CF.

NCT Number	NCT07223255
Lead Sponsor	Dartmouth-Hitchcock Medical Center Collaborators: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Conditions	Cystic Fibrosis (CF), Cystic Fibrosis Gastrointestinal Disease
Enrollment	20 participants
Start Date	2026-09-01
Primary Completion	2027-06 (estimated)
Study Completion	2027-06 (estimated)
Updated on ClinicalTrials.gov	2026-07-02