Clinical Trial

Impact of Smell Testing on Health Outcomes

Not Yet Recruiting Phase 2
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Summary
Smell dysfunction is frequent yet neglected. The sense of smell plays a crucial role in signaling disease, safety, and overall quality of life. However, the significance of a functional sense of smell in terms of health and well-being is often overlooked until one experiences a loss of smell due to injury or disease. Research demonstrates that individuals are often not self-aware of their smell dysfunction (i.e. they do not spontaneously report smell dysfunction as a symptom), especially if the changes are gradual, as in normal aging. Patients with smell dysfunction experience a marked reduction in quality of life, poor mental health, nutritional health, and brain health as well as increased 5- and 10-year mortality in older adults. This study explores whether or not enabling healthcare providers to offer resources and guidance on coping strategies for smell dysfunction improves health and wellbeing in those who experience it.
Trial Details
NCT Number NCT07222891
Lead Sponsor Monell Chemical Senses Center
Collaborators: National Institute on Deafness and Other Communication Disorders (NIDCD)
Conditions Olfactory Dysfunction, Wellbeing
Enrollment 1,000 participants
Start Date 2025-11-01
Primary Completion 2027-09-30 (estimated)
Study Completion 2027-11-30 (estimated)
Updated on ClinicalTrials.gov 2025-10-30