OER Glibenclamide for Neuropathic Pain in Multiple Sclerosis

This is an early phase safety evaluation of the use of oral extended release (OER) glibenclamide, which is otherwise known as glyburide, for use as a treatment for neurologic pain in people with multiple sclerosis. Patients will receive medication to assess safety and tolerability.

NCT Number	NCT07221799
Lead Sponsor	University of Maryland, Baltimore
Conditions	Multiple Sclerosis, Neuropathic Pain
Enrollment	10 participants
Start Date	2026-09-01
Primary Completion	2028-09-01 (estimated)
Study Completion	2029-09-01 (estimated)
Updated on ClinicalTrials.gov	2025-10-28