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Temporal Interference for Thalamocortical Activity and Network Modulation

Study acronym: TITAN
StatusRecruiting
PhasePhase 1
Started
View on ClinicalTrials.gov ↗
Trial flagged as At Risk
Primary completion moved at least 9 months later May 2027 → Mar 2028
See other at-risk trials from University of Wisconsin, Madison

Record History

See every version on ClinicalTrials.gov ↗

  1. Primary completion pushed from May 2027 to Mar 2028 Show 4 more changesShow less
    • Study completion pushed from Nov 2027 to Apr 2028
    • Eligibility criteria expanded, about 22 words
    • Secondary endpoints: details revised at 2 of 9 entries
    • Collaborators expanded, about 5 words
  2. Site contact updatedv9
  3. Enrollment increased: 30 → 40 participantsv8 Show 4 more changesShow less
    • Trial arms changed: 1 → 2
    • Interventions: Temporal Interference Transcranial electrical stimulation (TI-TES) (Device) to Sham stimulation (Device), Temporal Interference Transcranial electrical stimulation (TI-TES) (Device)
    • Eligibility criteria expanded, about 7 words
    • Study description expanded, about 2 words
  4. Re-verified, no change to tracked fieldsv7
  5. Trial status: Not Yet Recruiting to Recruiting
    • Start date changed from estimate of Dec 2025 to Dec 1, 2025
    • Site details revised
    v6
Show 4 earlier versionsHide 4 earlier versions
  1. Re-verified, no change to tracked fieldsv5
  2. Primary completion date: Apr 2027 to May 2027
    • Study completion date: Oct 2027 to Nov 2027
    • Start date: Nov 2025 to Dec 2025
    v4
  3. Start date: Oct 2025 to Nov 2025v3
  4. Re-verified, no change to tracked fieldsv2
  1. Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
The goal of this clinical trial is to find out whether a type of electrical brain stimulation, called temporal interference stimulation, can temporarily change the way different parts of the brain communicate with each other. Participants will: * Complete two stimulation phases - overnight and during wakefulness * Undergo two MRIs per study phase
Trial Details
NCT Number NCT07219719
Lead Sponsor University of Wisconsin, Madison
Collaborators: Brain & Behavior Research Foundation
Conditions
(from sponsor)		 Healthy Participants
Enrollment 40 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov