Clinical Trial

A Study to Investigate Bowel Cleansing With PLENVU® Compared to Sodium Picosulfate in Participants Aged 1 to < 18 Years of Age in Preparation for Colonoscopy

Study acronym: CLARITY
Recruiting Phase 3
View on ClinicalTrials.gov →
Summary
The purpose of the study is to assess the efficacy, safety and tolerability of PLENVU® by measuring its bowel cleansing success rate compared to sodium picosulfate in paediatric participants aged less than 18 years who are scheduled to undergo a colonoscopy. Colonoscopy is a crucial procedure that helps to diagnose and manage various gastrointestinal (GI) conditions in paediatric patients. An adequate level of bowel preparation and cleansing is essential for effective colonoscopy to allow proper visualisation of the bowel.
Protocol Amendment History 2 amendments
This ClinicalTrials.gov record has been amended 2 times since 2025-10-16; most recent amendment 2026-05-26.
Status change: Not Yet Recruiting → Recruiting 2026-01-19
Trial Details
NCT Number NCT07218523
Lead Sponsor Norgine
Collaborators: Parexel
Conditions Bowel Cleansing Prior to Clinical Procedures
Enrollment 212 participants
Start Date 2025-12-29
Primary Completion 2027-01-06 (estimated)
Study Completion 2027-01-06 (estimated)
Updated on ClinicalTrials.gov 2026-05-27