Clinical Trial

Safety and Efficacy of Injectable Klotho Plasmid Gene Therapy in Humans

Recruiting Phase 1
View on ClinicalTrials.gov →
Summary
The purpose of this study is to investigate the safety and efficacy of a gene therapy for Klotho, delivered via a nonviral plasmid in healthy adult volunteers. Additionally, this study seeks to understand the cognitive and health benefits of the Klotho gene therapy.
Protocol Amendment History 1 amendment
This ClinicalTrials.gov record has been amended once since 2025-10-10.
Trial Details
NCT Number NCT07216781
Lead Sponsor Minicircle
Conditions Healthy Adults
Enrollment 24 participants
Start Date 2025-10-06
Primary Completion 2026-08 (estimated)
Study Completion 2026-08 (estimated)
Updated on ClinicalTrials.gov 2026-02-17