Clinical Trial

Vape Use Among Younger & Older Smokers

Study acronym: ENDS
Active, Not Recruiting
View on ClinicalTrials.gov →
Record status
This record was last updated June 15, 2026 (before its estimated July 2026 completion). Its status may not reflect the trial's current state.
Summary
The study aims to recruit 100 current cigarette smokers (50 young adults ages 21-34; 50 older adults ages 35-65) who have tried vaping or are currently vaping (dual users). The study will examine the trajectories in tobacco use (cigarettes and/or ENDS), including the nuanced differences in ENDS use (i.e., detailed device characteristics, user preferences, patterns of use), according to smoker age group.
Protocol Amendment History 1 change
critical Trial status changed: Recruiting → Active, Not Recruiting 2026-06-16
Trial Details
NCT Number NCT07214168
Lead Sponsor Abramson Cancer Center at Penn Medicine
Collaborators: The Center for Coordination of Analytics, Science, Enhancement and Logistics (CASEL), Food and Drug Administration (FDA)
Conditions Smoking Cigarette, Smoking Behaviors, Vaping, Vaping Behaviors
Enrollment 100 participants
Start Date 2025-09-05
Primary Completion 2026-07 (estimated)
Study Completion 2026-07 (estimated)
Updated on ClinicalTrials.gov 2026-06-15