Clinical Trial

A Clinical Study to Evaluate the Stain Reduction Efficacy of a Non-Fluoride Tooth Whitening Dentifrice Containing Nano-Hydroxyapatite (nHAP) and a High Cleaning Silica Abrasive System Compared to a Commercial Fluoride Non-Whitening Dentifrice as a Negative Control

Completed
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Summary
To determine whether brushing with a non-fluoride tooth whitening dentifrice containing nHAP and a high cleaning silica system produces a greater level of stain reduction as indicated by the Modified Lobene Stain Index (MLSI) for the overall tooth surfaces than brushing with a commercial fluoride toothpaste for a period of 2 weeks.
Protocol Amendment History 1 change
critical Trial completed 2026-08-12
Trial Details
NCT Number NCT07214038
Lead Sponsor Boka LLC
Conditions Teeth Color, Teeth Staining
Enrollment 120 participants
Start Date 2025-09-01
Primary Completion 2025-10-01 (estimated)
Study Completion 2025-11-01 (estimated)
Updated on ClinicalTrials.gov 2026-08-11