Clinical Trial

CHAMPION: Combining HIV And Meth Prevention and Treatment Interventions Optimized for HIV-Negative MSM

Study acronym: CHAMPION
Not Yet Recruiting
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Record status
This record was last updated October 8, 2025 (before its estimated August 15, 2026 completion). Its status may not reflect the trial's current state.
Summary
The goal of this randomized controlled trial is to pilot test new mobile health (mHealth) interventions to improve PrEP adherence among HIV-negative men who have sex with men (MSM) with mild to moderate methamphetamine use disorder (MUD). The CHAMPION intervention combines two mHealth tools-PrEPAPP and CBT4CBT-to address both HIV prevention and MUD treatment needs in this population. The study's specific aims are: * To evaluate the feasibility and acceptability of the CHAMPION intervention based on treatment retention and engagement rates. * To examine the preliminary efficacy the CHAMPION intervention to improve PrEP adherence, as measured by dried blood spot (DBS) tests compared to the waitlist control group.
Trial Details
NCT Number NCT07213258
Lead Sponsor University of California, San Diego
Collaborators: National Institute on Drug Abuse (NIDA), University of California, San Francisco
Conditions PrEP Adherence, Methamphetamine Use Disorder, HIV
Enrollment 100 participants
Start Date 2025-10-22
Primary Completion 2026-08-15 (estimated)
Study Completion 2026-08-15 (estimated)
Updated on ClinicalTrials.gov 2025-10-08