Clinical Trial

Ayahuasca and Esketamine for Major Depression

Name: Ayahuasca and Esketamine for Major Depression — clinical trial record (NCT07212946)
Creator: DataLookout
License: https://creativecommons.org/licenses/by/4.0/

Completed Phase 2

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Summary

Double-blind, randomized trial comparing 4 weekly doses of oral ayahuasca and esketamine in patients with major depression.

Protocol Amendment History 1 amendment

This ClinicalTrials.gov record has been amended once since 2025-10-01.

Trial Details

NCT Number	NCT07212946
Lead Sponsor	University of Sao Paulo
Conditions	Major Depression Severe
Enrollment	22 participants
Start Date	2022-10-30
Primary Completion	2024-10-30 (estimated)
Study Completion	2025-10-01 (estimated)
Updated on ClinicalTrials.gov	2025-12-29