Clinical Trial

Low-Flow Desflurane Anesthesia and Its Effects on BIS and Postoperative Cognitive Functions

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Record status
This record was last updated December 9, 2025 (before its estimated December 20, 2025 completion). Its status may not reflect the trial's current state.
Summary
This study investigates the effects of low-flow desflurane anesthesia in adult patients undergoing major abdominal surgery. The researchers will examine whether different low-flow strategies: Cause differences in the Bispectral Index (BIS), which measures brain activity during anesthesia, Affect postoperative cognitive functions such as memory and attention. Participants will: Receive desflurane anesthesia during surgery, Have anesthesia delivered at different low-flow rates, Have their BIS values monitored throughout the operation, Complete tests after surgery to evaluate their cognitive functions. This research will help determine the safety of different low-flow strategies and their impact on patients' cognitive recovery after surgery.
Protocol Amendment History 1 amendment
This ClinicalTrials.gov record has been amended once since 2025-10-01.
Trial Details
NCT Number NCT07212543
Lead Sponsor Dolunay ARIK
Conditions Major Abdominal Surgeries
Enrollment 72 participants
Start Date 2025-05-15
Primary Completion 2025-12-20 (estimated)
Study Completion 2025-12-21 (estimated)
Updated on ClinicalTrials.gov 2025-12-09