Monitoring Coughs for the Early Detection of Worsening COPD

This study is for adults with COPD. Flare-ups of COPD, also known as exacerbations, can be serious and lead to hospital stays. The purpose of this research is to see if continuously and automatically monitoring a person's coughs can help predict these flare-ups early, before they become severe. Participants will use the Hyfe cough monitoring system, which includes a watch-like device worn on the wrist and a smartphone application. The system privately counts the number of coughs without recording any audio. Participants will also answer a short, weekly questionnaire about their COPD symptoms. This is an observational study, which means it will not change the regular medical care a participant receives. The participants and their care providers will not see the cough counts. The doctor will continue to manage their COPD as usual.

NCT Number	NCT07212439
Lead Sponsor	Clinica Universidad de Navarra, Universidad de Navarra Collaborators: Hyfe Inc
Conditions	Chronic Obstructive Pulmonary Disease (COPD)
Enrollment	50 participants
Start Date	2025-10-29
Primary Completion	2026-09 (estimated)
Study Completion	2026-09 (estimated)
Updated on ClinicalTrials.gov	2026-01-02