Clinical Trial

Early Predictors for Neurological Outcome After Traumatic Spinal Cord Injury

Study acronym: MurnauMAP
Active, Not Recruiting
View on ClinicalTrials.gov →
Summary
This project investigates early predictors of neurological recovery after traumatic spinal cord injury through three main aims: 1. MAP and vasopressors - determine whether continuous monitoring of mean arterial pressure (MAP) and the use of vasopressors in the ICU influence neurological outcome. 2. Pharmacological interventions - evaluate the impact of other medications, particularly opioids in the acute stage, on recovery. 3. Biomarkers - identify diagnostic and prognostic biomarkers (blood-borne or digital) from routine clinical measurements within the first year after injury. Using high-frequency ICU data and advanced data science methods, the study seeks to provide insights that support individualized treatment strategies and improve outcomes after SCI.
Trial Details
NCT Number NCT07210879
Lead Sponsor BG Unfallklinik Murnau
Collaborators: Foundation Wings For Life, University of California, San Francisco
Conditions Acute Traumatic Spinal Cord Injury
Enrollment 800 participants
Start Date 2022-07-20
Primary Completion 2025-06-30 (estimated)
Study Completion 2026-08-30 (estimated)
Updated on ClinicalTrials.gov 2025-10-07