Gingival Cleft Development at Two Time Points of Canine Retraction

The goal of this split-mouth randomized controlled trial is to assess whether the timing of extraction space closure-early vs. delayed initiation-affects the incidence of gingival cleft development in orthodontic patients. The main question it aims to answer is: Does the incidence of gingival cleft development get influenced by the specific time point at which orthodontic space closure is initiated following extraction? Quadrants will be assigned to the early movement group and the other to the delayed movement group and extractions will be performed accordingly. These will be assessed for the effect on development of gingival cleft development.

NCT Number	NCT07210762
Lead Sponsor	Bahria University
Conditions	Gingival Cleft, Orthodontic Space Closure
Enrollment	19 participants
Start Date	2025-10-15
Primary Completion	2026-03-19 (estimated)
Study Completion	2026-07-19 (estimated)
Updated on ClinicalTrials.gov	2025-10-07