Clinical Trial

Brazilian Multicenter Study on Esophageal Atresia

Study acronym: NEOBRA-EA
Not Yet Recruiting
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Summary
Esophageal atresia is a congenital malformation where the esophagus does not form properly, often associated with a tracheoesophageal fistula. This condition requires complex surgical treatment and intensive neonatal care. Survival has improved worldwide, but results from other countries cannot be directly applied to Brazil due to differences in health resources. This study will gather data from 72 neonatal centers across Brazil to better understand the characteristics, treatments, complications, and outcomes of newborns with esophageal atresia. The goal is to identify factors associated with complications and mortality, and to generate national evidence that can guide better care and improve survival and quality of life.
Trial Details
NCT Number NCT07210736
Lead Sponsor University of Sao Paulo General Hospital
Conditions Esophageal Atresia
Enrollment 1,000 participants
Start Date 2025-11-01
Primary Completion 2027-11-01 (estimated)
Study Completion 2027-12-01 (estimated)
Updated on ClinicalTrials.gov 2025-10-07