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Comparison of Submucosal Dexamethasone and Methylprednisolone in Postoperative Sequelae of Parasymphsis Fractures

StatusRecruiting
PhasePhase 2
Started
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Record History

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  1. 3 versions Re-verified since Jan 9, 2026, no change to tracked fieldsv4-v6
  2. Trial status: Not Yet Recruiting to Recruiting
    • Start date: Dec 1, 2025 to Jan 3, 2026
    • Study sites: 0 to 1
    v3
  3. Start date: Nov 1, 2025 to Dec 1, 2025v2 Show 4 more changesShow less
    • Primary completion date: Oct 30, 2026 to Nov 30, 2026
    • Study completion date: Nov 1, 2026 to Dec 1, 2026
    • Study title shortened, about 6 words
    • Study description shortened, about 2 words
  4. Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
The rationale of the current research is to address the limitation of existing knowledge as it is not clear which of the two drugs (Dexamethasone or Methylprednisolone) is more effective in reduction of postoperative sequelae in patient with mandibular parasymphysis fracture. This study fills the gap by providing sound evidence on the preferred steroid option to help clinicians have more data to make decisions and improve patients' health. The result of this research will then be added to the evidence-based protocols for the treatment of parasymphysis fractures.
Trial Details
NCT Number NCT07208799
Lead Sponsor Nishtar Medical University
Conditions
(from sponsor)		 Mandible Fracture, Edema Face, Pain Management, Corticosteroid Injection
Related terms Agnosia, Edema, Mandibular Fractures, Pain
Enrollment 72 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov