This is a first-in-human, Phase I, open-label, multi-center, dose-escalation and dose expansion study to evaluate the safety, tolerability, pharmacokinetics, and preliminary efficacy of JMKX005425 in subjects with microsatellite instability-high (MSI) and/or mismatch repair deficiency (dMMR) advanced solid tumors.
Protocol Amendment History
1 amendment
This ClinicalTrials.gov record has been amended once since 2025-09-28.
Status change: Not Yet Recruiting → Recruiting2025-11-27