Tianshan Community Cohort Establishment and Follow-up

This population-based cohort study on disease prevention and health promotion was established in northwest China, leveraging data from routine annual health examinations. Initiated in January 2016, the cohort enrolled nearly all residents aged 18 years and older who were registered at community healthcare centers. The program was developed to provide a comprehensive framework for disease prevention and community health promotion, with the aim of producing population-based evidence across a broad spectrum of diseases in the general population. At baseline, data were collected on participant demographics, medical and family histories, disability status, living environment, and blood biochemical parameters. Follow-up information is primarily obtained through chronic disease management programs, annual health examinations, and electrical health records. Cause-specific mortality is ascertained from local death registration systems. Biological specimens, questionnaire data, and electrical health records are systematically archived in the Biobank and Big Data Center of the People's Hospital of Xinjiang Uygur Autonomous Region.

NCT Number	NCT07207863
Lead Sponsor	People's Hospital of Xinjiang Uygur Autonomous Region Collaborators: People's Hospital of Hotan Prefecture, People's Hospital of Altay Prefecture, Luopu County People's Hospital of Hotan Prefecture, The First People's Hospital of Aksu Prefecture, Karamay Central Hospital of Xinjiang, People's Hospital of Kizilsu Kyrgyz Autonomous Prefecture, The Second People's Hospital of Kashgar Prefecture, RenJi Hospital
Conditions	Cohort Study, Natural Population, Northwest Region of China
Enrollment	1,000,000 participants
Start Date	2016-01-01
Primary Completion	2035-12-31 (estimated)
Study Completion	2035-12-31 (estimated)
Updated on ClinicalTrials.gov	2025-10-06