Clinical Trial

Nut Consumption and Prevention of Non-communicable Diseases: A Global Individual Participant Data Meta-analysis

Study acronym: NUTPOOL

Active, Not Recruiting

Record status

This record was last updated March 20, 2026 (before its estimated June 30, 2026 completion). Its status may not reflect the trial's current state.

Summary

The relationship between nut consumption and the risk of developing non-communicable diseases (NCDs) has been a subject of growing interest. However, the findings from previous studies have been conflicting for some health outcomes, such as type-2 diabetes, and have been underexplored for other outcomes, such as neurodegenerative diseases. One contributing factor to these inconsistencies lies in the different analytical approaches and confounding factors used across studies. Furthermore, the majority of previous studies have primarily focused on populations in Europe or the United States, potentially limiting the generalizability of the findings to other global regions. The NUTPOOL project aims to address these gaps by conducting an extensive individual participant data (IPD) meta-analysis. This study will evaluate the association between total and specific types of nut consumption and the future risk of NCDs.

Protocol Amendment History 1 amendment

This ClinicalTrials.gov record has been amended once since 2025-09-26.

Status change: Not Yet Recruiting → Active, Not Recruiting 2026-03-19

Trial Details

NCT Number	NCT07205978
Lead Sponsor	Institut Investigacio Sanitaria Pere Virgili Collaborators: University of Copenhagen
Conditions	Diabetes (DM), Cardio Vascular Disease, Cancer, Dementia, Dementia Alzheimer Type, Mortality, Parkinson Disease (PD), Death
Enrollment	1,000,000 participants
Start Date	2025-10-01
Primary Completion	2026-06-30 (estimated)
Study Completion	2027-01-30 (estimated)
Updated on ClinicalTrials.gov	2026-03-20