Utilization of Musculoskeletal Ultrasound to Detect Subclinical Findings in IBD Patients

Inflammatory bowel disease (IBD), including Crohn's disease and ulcerative colitis, frequently presents with musculoskeletal extraintestinal manifestations (EIMs), such as arthritis and enthesitis, affecting up to 50% of patients. These can be subclinical and are often underestimated by physical examination alone. Musculoskeletal ultrasound (MSK-US) is a sensitive, non-invasive tool for detecting both clinical and subclinical inflammation. Despite its benefits, there is no standardized MSK-US protocol specifically for IBD patients. This study aims to develop a structured MSK-US assessment protocol, evaluate its effectiveness in detecting musculoskeletal involvement, and investigate its relationship with IBD disease activity.

NCT Number	NCT07205549
Lead Sponsor	Assiut University
Conditions	IBD (Inflammatory Bowel Disease), Musculoskeletal Ultrasound
Enrollment	81 participants
Start Date	2025-10-01
Primary Completion	2025-11-30 (estimated)
Study Completion	2025-12-30 (estimated)
Updated on ClinicalTrials.gov	2025-10-03