Clinical Trial

Colonoscopic Detection of Phosphorylated Alpha-synuclein for Parkinson's Diagnosis

Study acronym: Syn-G

Recruiting

Summary

The goal of this observational study is to learn whether tissue samples taken from the colon during routine colonoscopy can detect signs of Parkinson's disease. The main question it aims to answer is: Can doctors find a protein called alpha-synuclein in colon tissue samples from people with Parkinson's disease? Currently, Parkinson's disease is diagnosed by observing symptoms like tremors and movement problems, but by then the disease has already progressed significantly. Earlier detection could help doctors start treatment sooner.

Protocol Amendment History 1 amendment

This ClinicalTrials.gov record has been amended once since 2025-09-24.

Trial Details

NCT Number	NCT07204652
Lead Sponsor	CND Life Sciences Collaborators: Oregon Health and Science University
Conditions	PARKINSON DISEASE (Disorder), Parkinson, Parkinson's Disease and Parkinsonism, Parkinson Disease
Enrollment	20 participants
Start Date	2025-09-03
Primary Completion	2028-09 (estimated)
Study Completion	2029-09 (estimated)
Updated on ClinicalTrials.gov	2026-02-11