Risk of Acute Complications With Rocuronium vs Cisatracurium in Patients With Chronic Kidney Disease

The purpose of the study is to determine which combination of neuromuscular blocking agent and reversal agent is safer to use during anesthesia for patients with chronic kidney disease. The main question it aims to answer is "The use of Cisatracurium with neostigmine leads to less post-operative pulmonary complications than Rocuronium with sugammadex."

NCT Number	NCT07203287
Lead Sponsor	The University of Texas Medical Branch, Galveston
Conditions	Post Operative Pulmonary Complications, Neuromuscular Blockade, General Anesthesia
Enrollment	490 participants
Start Date	2025-08-26
Primary Completion	2026-12-31 (estimated)
Study Completion	2027-08-26 (estimated)
Updated on ClinicalTrials.gov	2026-02-23