Clinical Trial

Circadian Health Regulation and Optimization for Rejuvenation Outcomes

Study acronym: CHRONO
Active, Not Recruiting
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Record status
This record was last updated December 31, 2025 (before its estimated April 1, 2026 completion). Its status may not reflect the trial's current state.
Summary
In this single arm intervention trial, the investigators will assess the impact of a personalized lifestyle plan, centered on supporting biological rhythms, on blood sugar levels, physical, cognitive and immune function in older adults with a habitual eating window of 12 hours or more, and elevated blood glucose levels. All participants will be provided with a personalized circadian rhythm optimization plan (CRO) centered on improving (1) diet, (2) exercise (3) sleep habits based on their body's natural rhythms. The study includes a 2-week screening/baseline assessments, with follow-up health assessments at 2-months.
Protocol Amendment History 1 amendment
This ClinicalTrials.gov record has been amended once since 2025-09-29.
Status change: Recruiting → Active, Not Recruiting 2025-12-23
Trial Details
NCT Number NCT07203196
Lead Sponsor Salk Institute for Biological Studies
Collaborators: University of California, San Diego
Conditions Aging, Healthy, Blood Sugar; High, Blood Sugar (Glucose) Control, Time Restricted Eating, Circadian Dysregulation
Enrollment 16 participants
Start Date 2025-10-22
Primary Completion 2026-04-01 (estimated)
Study Completion 2026-04-01 (estimated)
Updated on ClinicalTrials.gov 2025-12-31