A Multi-center Cohort Study of Hydatidiform Mole in China (CN-HM-01)

This observational study aims to establish a national cohort of patients with hydatidiform mole (molar pregnancy) to investigate its malignant transformation rate and malignant transformation mechanisms, with the goal of developing and promoting precision diagnosis and treatment models across China.

NCT Number	NCT07202728
Lead Sponsor	Obstetrics & Gynecology Hospital of Fudan University Collaborators: Peking Union Medical College Hospital, Shengjing Hospital, Hebei Medical University Third Hospital, Hainan women and children medical center, Shenzhen Maternity & Child Healthcare Hospital, Third Affiliated Hospital of Zhengzhou University, Shanghai First Maternity and Infant Hospital, International Peace Maternity and Child Health Hospital, Shandong University, First Affiliated Hospital of Zhejiang University, The Affiliated Hospital of Qingdao University, Gansu Provincial Maternal and Child Health Care Hospital, Dalian Women and Children's Medical Center
Conditions	Hydatidiform Mole
Enrollment	1,489 participants
Start Date	2025-07-09
Primary Completion	2028-08-30 (estimated)
Study Completion	2030-08-30 (estimated)
Updated on ClinicalTrials.gov	2025-10-02