Clinical Trial

Modulation of Motor Learning Via tDCS in a Dexterous Video Game Task

Terminated
View on ClinicalTrials.gov →
Why the trial stopped
An equivalence analysis demonstrated no statistical difference, and bayesian inference testing showed the potential for only a negligible effect.
Summary
The purpose of this study is to determine whether "transcranial direct current stimulation" (tDCS) is effective in enhancing learning of complex motor tasks of precision and accuracy that require the simultaneous coordination of both hands. The study will utilize a between-subjects, SHAM controlled design. Subjects will be randomly selected to receive either SHAM (n=26) or a-tDCS (n=26) stimulation and will be blinded to their condition throughout testing. Subjects will complete a total of two testing sessions, separated by \~24 hours. Both sessions will have the subject play the videogame "Guitar Hero", with a single song done for several trials as pre- and post-assessments. The first session will contain a 20-minute practice/stimulation block where subjects practice the guitar task while receiving either "active" or "inactive" stimulation of the motor cortex. The first session will last approximately 75 to 90 minutes whereas the second session will last approximately 15 to 20 minutes.
Protocol Amendment History 5 changes
critical Trial terminated 2026-06-02
critical Reason stopped changed: — → An equivalence analysis demonstrated no statistical difference, and bayesian inference testing showed the potential for only a negligible effect. 2026-06-02
notable Enrollment reduced: 52 -> 40 participants 2026-06-02
notable Primary completion moved earlier: 2027-03-03 -> 2025-12-03 2026-06-02
minor Completion moved earlier: 2027-03-03 -> 2025-12-03 2026-06-02
Trial Details
NCT Number NCT07202702
Lead Sponsor Indiana University
Conditions Motor Activity
Enrollment 40 participants
Start Date 2025-04-04
Primary Completion 2025-12-03 (estimated)
Study Completion 2025-12-03 (estimated)
Updated on ClinicalTrials.gov 2026-06-01