Open-label Randomized Controlled Trial of Two Protocols for Weaning From High Frequency Oscillatory Ventilation in Preterm Neonates With Respiratory Distress Syndrome Admitted in the NICU of Mansoura University Children Hospital

Our study is a randomized controlled trial that compares two weaning protocols of preterm infants with respiratory distress syndrome who are ventilated on high frequency oscillatory ventilation in order to establish the best weaning strategy with the least complications possible for this group of patients.

NCT Number	NCT07202299
Lead Sponsor	Mansoura University Children Hospital
Conditions	Respiratory Distress Syndrome (Neonatal)
Enrollment	110 participants
Start Date	2025-09-22
Primary Completion	2027-03 (estimated)
Study Completion	2027-09 (estimated)
Updated on ClinicalTrials.gov	2025-10-01