Clinical Trial

Biomarkers of Inflammation and Fibrosis in Conduction Disorders After TAVI

Recruiting
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Record status
This record was last updated October 6, 2025 (before its estimated April 2026 completion). Its status may not reflect the trial's current state.
Summary
Prediction of conduction disorders (CDs) in patients with severe aortic stenosis (AS) undergoing transcatheter aortic valve implantation (TAVI) is an important and complex process with a significant impact on patient outcomes. The goal of this observational prospective trial is to investigate the role of pre-procedural values of systemic biomarkers of inflammation and fibrosis in the prediction of new-onset CDs and permanent pacemaker implantation (PPI) in patients undergoing the TAVI procedure.
Protocol Amendment History 1 amendment
This ClinicalTrials.gov record has been amended once since 2025-09-30.
Trial Details
NCT Number NCT07201363
Lead Sponsor Clinical Hospital Center Rijeka
Collaborators: University of Rijeka
Conditions TAVI(Transcatheter Aortic Valve Implantation), Conduction Disorder, Aortic Stenosis, Permanent Pacemaker Implantation
Enrollment 102 participants
Start Date 2024-12-12
Primary Completion 2026-04 (estimated)
Study Completion 2026-08 (estimated)
Updated on ClinicalTrials.gov 2025-10-06