Meloxicam in Mohs Micrographic Surgery

The goal of this clinical trial is to explore alternative methods of postoperative pain control in Mohs micrographic surgery. The main aims are: * To provide more information to the Mohs surgery community regarding postoperative pain control. * Reducing pain improves the overall comfort and well-being of patients, leading to a better post-operative experience. * To provide patients with an alternative and potentially superior NSAID for pain control (compared to standard-of-care ibuprofen). Researchers will compare 1) a single of dose Meloxicam 7.5 mg, followed by acetaminophen 500 mg; 2) a single dose of Meloxicam 15 mg, followed by acetaminophen 500 mg; 3) a single dose of acetaminophen 500 mg, followed by alternating ibuprofen 200 mg and acetaminophen 500 mg to see which better moderate pain control and patient satisfaction. Participants will be asked to complete pain and patient satisfaction surveys.

NCT Number	NCT07200544
Lead Sponsor	University of Oklahoma
Conditions	Postoperative Pain, Acute, Skin Cancer
Enrollment	300 participants
Start Date	2025-10-15
Primary Completion	2026-06-02 (estimated)
Study Completion	2026-08-02 (estimated)
Updated on ClinicalTrials.gov	2025-12-15