Strengthening HPV Vaccination and Adolescent Health Research Program in Nigeria (SHARP)

The goal of this clinical trial is to learn whether adding adolescent health services to routine government health programs can increase Human Papillomavirus (HPV) vaccination coverage among 9-year-old girls and improve use of other health services by adolescents in Nigeria. The main questions it aims to answer are: Does offering an integrated package of adolescent health services increase the proportion of 9-year-old girls who receive the HPV vaccine? Does this package increase use of other services such as reproductive health counseling, nutrition and vision screening, mental health services, and deworming among girls and boys ages 9-15 years? Researchers will compare areas that receive the integrated package to areas that continue with the standard government services to see if the intervention improves vaccination and health service use. Participants will: Be surveyed about HPV vaccination and health service use before and after the program is offered. Take part in interviews or focus groups about experiences with adolescent health services. Be offered HPV vaccination and other adolescent health services through local health facilities.

NCT Number	NCT07200414
Lead Sponsor	Johns Hopkins Bloomberg School of Public Health Collaborators: Direct Consulting and Logistics, Jhpiego, Gavi, The Vaccine Alliance
Conditions	Human Papillomavirus (HPV) Vaccine, Human Papillomavirus (HPV) Vaccines, Human Papillomavirus (HPV) Infections, Adolescent Health Services
Enrollment	12,654 participants
Start Date	2024-10-01
Primary Completion	2025-12-31 (estimated)
Study Completion	2025-12-31 (estimated)
Updated on ClinicalTrials.gov	2026-04-13