A Multi-Center Study Assessing the Safety and Efficacy of the LEGION Medial Stabilized (MS) Insert in Patients Undergoing a Total Knee Arthroplasty (TKA)

The purpose of this study is to assess the long-term safety and performance of the LEGION Medial Stabilized insert and to generate clinical evidence to support and maintain product registration in global markets.

NCT Number	NCT07199738
Lead Sponsor	Smith & Nephew, Inc.
Conditions	Inflammatory Arthritis, Primary Total Knee Arthroplasty Due to Degenerative Joint Disease (Primary Diagnosis of Osteoarthritis), Post-traumatic Arthritis
Enrollment	144 participants
Start Date	2025-09-25
Primary Completion	2036-12 (estimated)
Study Completion	2036-12 (estimated)
Updated on ClinicalTrials.gov	2026-08-06