Accelerated rTMS Therapeutic Approach for Refractory Obsessive-Compulsive Disorder

The goal of this clinical trial is to learn if individualized accelerated repetitive transcranial magnetic stimulation (rTMS) targeting the inferior frontal cortex combined with symptom provocation works to treat obsessive-compulsive disorders (OCD) in adults. It will also learn about the safety of rTMS over right IFC. The main questions it aims to answer are: * Does rTMS using a new individualized IFC target relieve participants' OCD symptoms? * What medical problems do participants have when taking rTMS? Participants will: * Take rTMS six times per day for 5 consecutive days * Visit the clinic once at baseline, the day and four weeks after treatment for checkups and tests

NCT Number	NCT07198594
Lead Sponsor	Shanghai Pudong New Area Mental Health Center, School of Medicine, Tongji University
Conditions	Obsessive Compulsive Disorder (OCD), Obsessive - Compulsive Disorder
Enrollment	20 participants
Start Date	2025-07-03
Primary Completion	2026-12-31 (estimated)
Study Completion	2027-12-31 (estimated)
Updated on ClinicalTrials.gov	2025-09-30