Clinical Trial

Cryotherapy as a Topical Anesthetic in Healthy Children

Completed Phase 4
View on ClinicalTrials.gov →
Summary
In this study, the investigators aimed to compare the effects of topical anesthetic materials and cold application on pain perception. The main questions it aims to answer are: * Is cold application is effective as a topical anesthetic replacement? * Is there a difference on pain perception between cold and room temperature topical anesthetic? The treatment contains of participants selected from a group of patients who requires dental treatment. The mission of the participants is to answer the questionnaires correctly and cooperate the treatment. Participants will be divided into 4 groups containing 25 child per group: * First group: topical anesthetic spray solution. * Second group: topical anesthetic gel * Third group: Cryotherapy as distilled water * Fourth group: Cryotherapy as topical anesthetic spray solution. All participants will answer questionnaire of pain, anxiety and taste. The oxygen saturation and pulses will be measured with a pulse-oxymeter device to be recorded.
Protocol Amendment History 1 amendment
This ClinicalTrials.gov record has been amended once since 2025-09-25.
Status change: Active, Not Recruiting → Completed 2026-02-05
Trial Details
NCT Number NCT07198022
Lead Sponsor Ondokuz Mayıs University
Conditions Healthy, Topical Anesthesia, Pediatric Dentistry, Cryotherapy
Enrollment 100 participants
Start Date 2025-09-01
Primary Completion 2026-01-15 (estimated)
Study Completion 2026-01-15 (estimated)
Updated on ClinicalTrials.gov 2026-02-09