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2-HOBA Supplementation in People With Elevated Lipoprotein(a)

StatusNot Yet Recruiting
PhaseNot applicable
Started
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Record status
This record was last updated September 30, 2025 (before its estimated March 2026 completion). Its status may not reflect the trial's current state.

Record History

  1. Study First Submitted
The goal of this clinical trial is to learn if a natural supplement called 2-hydroxybenzylamine (2-HOBA) can reduce harmful oxidized lipids and improve the function of lipoprotein(a) in adults with high lipoprotein(a) levels. The main questions it aims to answer are: Does 2-HOBA lower oxidized phospholipids on lipoprotein(a)? Does 2-HOBA reduce markers of inflammation and blood clotting in the blood? Participants will: Take 2-HOBA capsules (400 mg, three times daily with meals) for 6 weeks Provide blood and urine samples at the beginning, middle, and end of the study Have lab tests to measure changes in lipids, inflammation, and clotting markers
Trial Details
NCT Number NCT07198009
Lead Sponsor The Miriam Hospital
Conditions
(from sponsor)		 Hyperlipidemia, Elevated Lp(a)
Related terms Hyperlipidemias
Enrollment 10 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov