Healing After Endodontic Microsurgery Using a Rotary Bur Versus Piezoelectric Unit for Osteotomy and Root Resection

The goal of this clinical trial is to compare bone healing after using apical tooth microsurgery to remove root end infection, either by use of rotary burs for cutting bone and root end, or by use of piezoelectric surgery for the same procedures. The main questions it aims to answer are: * Is there a difference in bone healing and reformation between the two surgical procedures ? * Is there a difference in bone healing between cutting the bone with a rotary bur and cutting the bone with the 'bone window' technique that uses piezoelectric unit ?

NCT Number	NCT07197658
Lead Sponsor	National and Kapodistrian University of Athens
Conditions	Periapical Periodontitis, Endodontic Microsurgery, Osteotomy
Enrollment	124 participants
Start Date	2023-04-25
Primary Completion	2026-05-11 (estimated)
Study Completion	2026-12-10 (estimated)
Updated on ClinicalTrials.gov	2026-06-08