Clinical Trial

Double-Layer Closure Technique Using Buccal and Palatal Flaps for Oroantral Fistula

Study acronym: OAF-DLC
Enrolling by Invitation
View on ClinicalTrials.gov →
Record status
This record was last updated September 29, 2025 (before its estimated December 10, 2025 completion). Its status may not reflect the trial's current state.
Summary
A prospective clinical case series was conducted involving twelve patients with oroantral fistulas ≥5 mm in diameter. Closure was performed using split-thickness buccal and palatal mucosal flaps with a subepithelial palatal connective tissue graft rotated to cove the bony defect and sutured to the buccal periosteum as the first layer, then the buccal mucosa sutured with the palatal one . Clinical evaluations were conducted at regular intervals over a 3-month postoperative period, assessing wound healing, fistula recurrence, pain, facial edema, infection, and donor site morbidity.
Trial Details
NCT Number NCT07196566
Lead Sponsor Tanta University
Conditions Oroantral Fistula, Double Layer
Enrollment 12 participants
Start Date 2025-07-28
Primary Completion 2025-12-10 (estimated)
Study Completion 2025-12-30 (estimated)
Updated on ClinicalTrials.gov 2025-09-29